Kyriaki Sidiropoulou,PhD

Assistant Professor

Department of Biology –

University of Crete

Affiliated researcher, Institute of Molecular Biology and Biotechnology - FORTH

Email: Αυτή η διεύθυνση ηλεκτρονικού ταχυδρομείου προστατεύεται από τους αυτοματισμούς αποστολέων ανεπιθύμητων μηνυμάτων. Χρειάζεται να ενεργοποιήσετε τη JavaScript για να μπορέσετε να τη δείτε.

Tel: 2810394071

Lab web page: www.sidiropouloulab.com

Education

Year

1998            BS in Microbiology and Physiology, Sourthern Illinois University at Carbondale

2003            PhD in Neuroscience, Rosalind Franklin of Health and Sciences/The Chicago Medical School

2003-2005  Postdoctoral Fellow, School of Medicine, University of Crete (Venetia Zachariou)

2005-2010 Postdoctoral Fellow, IMBB-FORTH, Dr. Yiota Poirazi

Research Interests

My research aims to understand the development of neurophysiological mechanisms underlying cognitive processes, such as working memory and long-term memory, to identify predictive changes in biophysical mechanisms in disease-states and test therapeutic regimens to prevent the emergence of neuropsychiatric symptoms. We use a multi-disciplinary approach, including behavioural tests, in vivo manipulations patch-clamp recordings from brain slices, field recordings from brain slices, biochemistry, histology and computational approaches.

Funding 

• Special Accounts for Research, University of Crete, large grants type C award, Title: “The effects of working memory training on cognitive flexibility and underlying neurobiological substrates in man and mouse: A translational study” (2019-2021)

Recent Publications or Selected Publications

1. K. Chalkiadaki, A. Velli, E. Kyriazidis, V. Stavroulaki, A. Chatzaki, M. Aivaliotisand K. Sidiropoulou (2018) Development of the MAM model of schizophrenia in mice: Sex similarities and differences in hippocampal and prefrontal cortical function, Neuropharmacology,2018 Oct 23. pii: S0028-3908(18)30813-X. doi: 10.1016/j.neuropharm.2018.10.026. [Epub ahead of print]

2. X. Konstantoudaki, K. Chalkiadaki, E. Vassileiou, K. Kalemaki, D. Karagogeos and K. Sidiropoulou (2018) Prefrontal cortical specific differences in behavior and synaptic plasticity between adolescent and adult mice, Journal of Neurophysiology, Mar 1;119(3):822-833. doi: 10.1152/jn.00189.2017. Epub 2017 Nov 22.

3. V. Nikelotopoulou, K. Sidiropoulou, E. Kallergi, Y. Dalezios and N. Tavernarakis, BDNF regulates autophagy in the adult brain to coordinate metabolic status and adaptive behavior (2017), Cell Metabolism,Jul 5;26(1):230-242.e5. doi: 10.1016/j.cmet.2017.06.005

4. X. Konstantoudaki, K. Chalkiadaki, S. Tivodar, D. Karagogeosand K. Sidiropoulou (2016) Impaired synaptic plasticity in the prefrontal cortex of mice with developmentally decreased numbers of interneurons, Neuroscience. 2016 Feb 26. pii: S0306-4522(16)00188-3. doi: 10.1016/j.neuroscience.2016.02.048.

5. X. Konstantoudaki, A. Papoutsi, K. Chalkiadaki, P. Poirazi and K. Sidiropoulou (2014) Modulatory effects of inhibition in a cortical microcircuit model, Frontiers in Neural Circuits, 8:7. doi: 10.3389/fncir.2014.00007.