Ioannis Charalampopoulos, PhD

Assistant Professor

School of Medicine / Department of Pharmacology

University of Crete

Affiliated Researcher, Institute of Molecular Biology & Biotechnology - FORTH

Email: This email address is being protected from spambots. You need JavaScript enabled to view it. / This email address is being protected from spambots. You need JavaScript enabled to view it.

Tel: 2810394531

Lab web page: http://regenera-pharm.med.uoc.gr / http://www.imbb.forth.gr/en/research-en/neurosciences/item/3677-ioannis-charalampopoulos

Education

1996 BS in Biology, University of Patras
2000 MA in Neuroscience, University of Crete
2004 PhD in Neuropharmacology, School of Medicine , University of Crete
2007 Postdoctoral Fellow at Karolinska Institute

Research Interests

We are focusing our research interests on the investigation of the molecular mechanisms that neurotrophic factors and their receptors are using to regulate the regenerative capacity of the adult nervous system. Neurotrophins, control brain development and maintenance during adulthood and in aging, while they importantly participate in neuronal survival, differentiation and repair. Our studies are ranging from neurotrophin receptors’ signaling to adult hippocampal neurogenesis to development of novel ligands with specific effects on these receptors (mainly the Trks and p75^NTR receptors) and their therapeutic potential on animal models of neurodegenerative diseases (Alzheimer’s Disease).

Funding

European Commission, Marie Sklodowska Curie Actions - Innovative Training Networks (ITN). Call: H2020-MSCA-ITN-2017, National Funding: Call for Operational Programme 'Competitiveness, Entrepreneurship and Innovation’ (GSRT). Grants from Niarchos and Bodossakis Foundations

Selected Publications

Pediaditakis I, Kourgiantaki A, Prousis KC, Potamitis C, Xanthopoulos KP, Zervou M, Calogeropoulou T, ^# Charalampopoulos I, Gravanis A. Front Pharmacol . 2016. 7:512.

Pediaditakis I, Efstathopoulos P, Prousis KC, Zervou M, Arévalo JC, Alexaki VI, Nikoletopoulou V, Karagianni E, Potamitis C, Tavernarakis N, Chavakis T, Margioris AN, Venihaki M, Calogeropoulou T, ^#Charalampopoulos I, Gravanis A. Neuropharmacology . 2016. 111:266-282.

Efstathopoulos P, Kourgiantaki A, Karali K, Sidiropoulou K, Margioris AN, Gravanis A, ^#Charalampopoulos I.Transl Psychiatry . 2015. 5:e685

Charalampopoulos I, Vicario A, Pediaditakis I, Gravanis A, Simi A, Ibáñez CF. Cell Rep. 2012.2(6):1563-70.

Vilar M*, Charalampopoulos I*,Kenchappa RS*, Simi A*, Karaca E, Reversi A, Choi S, Bothwell M, Mingarro I, Friedman W, SchiavoG, BastiaensP, VerveerP, CarterBD, IbáñezCF. Neuron, 2009, 62(1): 72-83 (* equal contributors)
(# Corresponding author).